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Title   하인두암의 방사선치료 ( Management of Hypopharyngeal Carcinoma )
Publicationinfo   1996 Jan; 028(05): 813-819.
Key_word   Hypopharyngeal carcinoma, Radiotherapy only, Combination therapy
Full-Text  
Abstract   Fifty-nine patients with squamous cell carcinoma of the hyphopharynx were treated at Seoul National University Hospital between October 1979 and December 1992. Of these, l8 patients received radiotherapy alone, 17 patients received planned surgery with neck dissection, followed by post-operative radiotherapy, and 24 patients received radiotherapy following 2 or 3 cycles of FP chemotherapy. A median follwo-up period was 41 months, ranged from 25 months to 129 months. The majority of the patients(94.9%, 56/59) was diagnosed with stage III(19%) or IV(75.9%). The overall survival at 5 years for all patients was 29%,with a median survival of 29 months. The 5-year survival rate was 15% on radiotherapy alone, 35% on surgery and postoperative radiotherapy, and 33% on 2 cyles of FP regimens followed by radiotherapy(p=0.001). However, the survival rates between surgery plus postoperative radiotherapy and chemotherapy following radiotherapy was not statistically significant, but voice preservation and swallowing function is superior with chemotherapy following radiotherapy. Although there was no randomized studies of surgery and postoperative radiotherapy versus chemothrapy following radiotherapy, nonsurgical management of advanced hypopharyngeal cancer employing chemothrapy and radiotherapy is preferred to radical surgery for patients with squamous cell carcinoma of the hypopharynx.
저 자   우홍균(Hong Gyun Wu),유형준(Hyung Joon Yoo),박찬일(Charn Il Park),김광현(Kwang Hyun Kim),조용갑(Young Kap Cho)